Category: FOXO

  • Rhodiola rosea extends lifespan in silkworm

    Rhodiola rosea extends lifespan in silkworm

    The study identified 17 Fox genes in the silkworm, classified into 13 subfamilies. The genes have varied expression patterns in larval tissues and play roles in cellular components and biological processes. Purifying selection acts on most amino acid sites.

  • Identify silkworm FOX transcription factor family

    Identify silkworm FOX transcription factor family

    The study identified 17 Fox genes in the silkworm, classified into 13 subfamilies. The genes have varied expression patterns in larval tissues and play roles in cellular components and biological processes. Purifying selection acts on most amino acid sites.

  • Juvenile hormone shortens silkworm lifespan

    Juvenile hormone shortens silkworm lifespan

    The study showed that juvenile hormone (JH) and its analog can shorten the survival of male silkworm, while allatostatin, which inhibits JH secretion, extends survival. JH reduces a pro-longevity transcription factor, FoxO, and regulates it through a JH response element. A JH-binding protein, BmTO, functions as a target of FoxO,…