Category: silkworm model
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Salidroside promotes healthy longevity
The study investigates the impact of salidroside (SA) from Rhodiola rosea on lifespan and healthspan. SA binds to HSP90, reducing oxidation and extending lifespan. It inhibits HSP90’s ATPase activity, affecting protein interaction and gene expression. This reveals SA’s potential as an anti-aging drug and antioxidative agent, crucial for human health.
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Lycium barbarum polysaccharide improves Parkinson’s in silkworm
The study identified 17 Fox genes in the silkworm, classified into 13 subfamilies. The genes have varied expression patterns in larval tissues and play roles in cellular components and biological processes. Purifying selection acts on most amino acid sites.
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Rhodiola rosea extends lifespan in silkworm
The study identified 17 Fox genes in the silkworm, classified into 13 subfamilies. The genes have varied expression patterns in larval tissues and play roles in cellular components and biological processes. Purifying selection acts on most amino acid sites.
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Identify silkworm FOX transcription factor family
The study identified 17 Fox genes in the silkworm, classified into 13 subfamilies. The genes have varied expression patterns in larval tissues and play roles in cellular components and biological processes. Purifying selection acts on most amino acid sites.
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Juvenile hormone shortens silkworm lifespan
The study showed that juvenile hormone (JH) and its analog can shorten the survival of male silkworm, while allatostatin, which inhibits JH secretion, extends survival. JH reduces a pro-longevity transcription factor, FoxO, and regulates it through a JH response element. A JH-binding protein, BmTO, functions as a target of FoxO,…
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Astragalus polysaccharide extends lifespan in silkworm
A study in Aging and Disease 2019 reveals that Astragalus polysaccharide (APS) extends the silkworm’s lifespan by mitigating endoplasmic reticulum stress. APS increases lifespan and body weight, enhances antioxidant enzyme activities, and rescues lifespan from infection. It also ameliorates endoplasmic reticulum stress. The findings shed light on APS-induced lifespan extension…